Synthego is searching for a Research Associate to join our Engineered Cells Operations team and help create the world’s first fully automated Genome Engineering lab.
This position has shift options available:
– Tuesday through Saturday; 2:30PM-11PM
– Sunday through Thursday; 2:30PM-11PM
– Tuesday through Saturday; 6:30AM- 3PM
What You’ll Do

• Engineer immortalized and/or hiPSC cells using CRISPR-Cas9, ultimately generating a pool or clonal population
• Perform daily cell culture tasks including feeds, expands, and cryopreservation
• Operate laboratory automation (liquid handling systems, clonal expansion systems)
• Perform daily operational checks, calibrations, and maintenance as required
• Extract genomic DNA, perform PCR assembly, and analyze samples using gel electrophoresis
• Review Sanger Sequencing data and determine next steps in the manufacturing process
• Receive and prepare laboratory reagents; update LIMS during the manufacturing process
• Maintain laboratory inventory, equipment, record-keeping and administrative tasks for cell line maintenance and related projects
• Draft and revise manufacturing standard operating procedures (SOPs) and work instructions (WIs)
• Perform laboratory cleaning and maintenance as per rotation schedule
• Acquire and analyze microscopy images
• Participate in company meetings and present data and project plans
• Work closely with Process Engineering to define user requirements for new technologies and to execute performance qualification (PQ) experiments

About You

• BS in molecular and cell biology and biology or related field
• Minimum of 1 year of cell culture experience
• Experience working with a variety of immortalized lines
• Excellent aseptic technique and understanding of contamination control
• Strong organizational, time management, and interpersonal skills
• Excellent verbal and written communication skills
• Ability to work cross functionally with various personas
• Team player who thrives in a fast paced environment

Nice to Haves

• Experience with transfections and genetic engineering of mammalian cells
• Direct experience handling induced pluripotent stem cells (iPSC) or primary cells
• Experience with flow cytometry
• Familiarity with Laboratory Information Management Systems (LIMS)

Company Benefits & Perks

• Competitive salary
• Generous equity at an early stage company
• Robust medical, dental and vision benefits
• 401k Plan
• Fully stocked kitchen and snacks
• Free catered lunches and dinners
• Onsite gym
• Daily shuttle bus to & from San Francisco